Author

Meng Huang

University of North Texas Health Science CenterORCID 0000-0001-7295-9788Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Genetics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Research Focus:benchmarking· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Bruce BudowleiD· 2 shared Chengming ZhuiD· 2 shared Jianye GeiD· 2 shared Minjie HongiD· 2 shared Shouhong GuangiD· 2 shared Xiangyang CheniD· 2 shared Xinhao HouiD· 2 shared Xuezhu FengiD· 2 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

Bruce BudowleORCID

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5 papers

Recent·Most cited

GeneticsbioRxivPreprintMar 26, 2026

Identification of a somatic H3K23me3 methyltransferase SET-19 in C. elegans

Mingjing Xu, Zixue Fan, Chaoyue Yan…·Xuezhu Feng

This study identifies SET-19 as a somatic H3K23 methyltransferase in C. elegans and shows its role in gene repression through chromatin modifications.

DOI 10.64898/2026.03.24.713969

C. elegansproteomics

𝕏 PostBluesky

BioinformaticsbioRxivPreprintFeb 15, 2023

Precise and ultrafast tandem repeat variant detection in massively parallel sequencing reads

Xuewen Wang, Meng Huang, Bruce Budowle, Jianye Ge

TRcaller detects tandem repeat alleles from short- and long-read sequences with higher accuracy and speed than existing tools.

2 citations

whole-genome sequencingexperimental assay

𝕏 PostBluesky

GeneticseLifePeer-reviewedSep 20, 2022

H3K9me1/2 methylation limits the lifespan of C. elegans

Meng Huang, Minjie Hong, Xinhao Hou…·Xuezhu Feng

This study shows that mutations in H3K9me1/2 methyltransferase genes synergistically extend lifespan in C. elegans daf-2 mutants, enhancing stress resistance through DAF-16 activation.

32 citations

C. elegansstatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMar 28, 2022

vcferr: Development, Validation, and Application of a SNP Genotyping Error Simulation Framework

VP Nagraj, Matthew B. Scholz, Shakeel Jessa…·Stephen Turner

vcferr simulates SNP genotyping errors in VCF files to assess their impact on kinship analysis.

1 citation

whole-exome sequencingsimulation

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GenomicsGigaSciencePeer-reviewedDec 11, 2018

BLINK: A Package for Next Level of Genome Wide Association Studies with Both Individuals and Markers in Millions

Meng Huang, Xiaolei Liu, Yao Zhou…·Zhiwu Zhang

BLINK improves statistical power and reduces computing time for GWAS by replacing FarmCPU's bin method with Bayesian information criteria and linkage disequilibrium information.

871 citationstop 1%

GWAS summary statisticsstatistical model

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