Author

Mingjing Xu

University of Science and Technology of China

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 4 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Chengming ZhuiD· 4 shared Shouhong GuangiD· 4 shared Xuezhu FengiD· 4 shared Jiewei ChengiD· 3 shared Xinhao HouiD· 3 shared Xinya HuangiD· 3 shared Jianing GaoiD· 2 shared Minjie HongiD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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4 shared papersGenetics

Chengming ZhuORCID

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4 papers

Recent·Most cited

Identification of a somatic H3K23me3 methyltransferase SET-19 in C. elegans

Mingjing Xu, Zixue Fan, Chaoyue Yan, Xiangyang Chen, Xinya Huang, Chengming Zhu, Minjie Hong, Jiewei Cheng, Xinhao Hou, Shuju Li, Mengfeng Li, Yunyu Shi, Meng Huang, Shouhong Guang, Xuezhu Feng

This study identifies SET-19 as a somatic H3K23 methyltransferase in C. elegans and shows its role in gene repression through chromatin modifications.

bioRxiv · Mar 26, 2026 · PreprintGenetics

Spatially clustered piRNA genes promote the transcription of piRNAs via condensate formation of the H3K27me3 reader UAD-2

Chengming Zhu, Xiaoyue Si, Xinhao Hou, Panpan Xu, Jianing Gao, Yao Tang, Chenchun Weng, Mingjing Xu, Qi Yan, Qile Jin, Jiewei Cheng, Ke Ruan, Ying Yin Zhou, Ge Shan, Demin Xu, , Shouhong Guang

The paper shows that spatial clustering of piRNA genes in nematodes enhances transcription through phase separation involving UAD-2 and the SUMO regulatory factors GEI-17 and TOFU-3.

Nature Structural & Molecular Biology · May 2, 2025Peer-reviewedMolecular Biology

Peri-centrosomal localization of small interfering RNAs in C. elegans

Qile Jin, Xuezhu Feng, Minjie Hong, Ke Wang, Xiangyang Chen, Jiewei Cheng, Yan Kuang, Xiaoyue Si, Mingjing Xu, Xinya Huang, Shouhong Guang, Chengming Zhu

The paper identifies peri-centrosomal localization of siRNAs in C. elegans using NRDE-3 as a reporter, showing dependence on 22G siRNAs and centrosomal components.

bioRxiv · Jul 11, 2024 · PreprintGenetics

Systematic characterization of chromodomain proteins revealsan H3K9me1/2 reader regulating aging in C. elegans

Xinhao Hou, Mingjing Xu, Chengming Zhu, Jianing Gao, Meili Li, Xiangyang Chen, Cheng Sun, Björn Nashan, Jianye Zang, Ying Zhou, Shouhong Guang, Xuezhu Feng

The paper systematically characterizes chromodomain proteins in C. elegans, identifying CEC-5 as an H3K9me1/2 reader that regulates aging through interactions with MET-2.

Nature Communications · Mar 6, 2023Peer-reviewedMolecular Biology