Author

Robert G. Nelson

National Institute of Diabetes and Digestive and Kidney DiseasesORCID 0000-0001-7307-3786Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Matthias KretzleriD· 4 shared Viji NairiD· 4 shared Alexander Peter MaxwelliD· 3 shared Amy Jayne McKnightiD· 3 shared Carol M. ForsblomiD· 3 shared Catherine GodsoniD· 3 shared Eoin Patrick BrennaniD· 3 shared Gareth J. McKayiD· 3 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMolecular Biology

Matthias KretzlerORCID

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4 papers

Recent·Most cited

Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathy

Shuya Liu, Yu Zhao, Shun Yan Lu, Tianran Zhang, Maja T. Lindenmeyer, Viji Nair, Sydney Elisabeth Gies, Guochao Wu, Robert G. Nelson, Jan Czogalla, Hande Aypek, Stephanie Zielinski, Zhouning Liao, Melanie Schaper, Damian Fermin, , Tobias Bruno Huber

This study uses single-cell RNA sequencing to identify a mechanosensitive MRTF-SRF pathway in early diabetic nephropathy, validated in human datasets and ex vivo experiments.

Genome Medicine · Jan 10, 2023Peer-reviewedMolecular Biology

Genome-wide meta-analysis and omics integration identifies novel genes associated with diabetic kidney disease

Niina Sandholm, Joanne B. Cole, Viji Nair, Xin Sheng, Hongbo Liu, Emma Ahlqvist, Natalie R. van Zuydam, Emma H. Dahlström, Damian Fermin, Laura Jane Smyth, Rany M. Salem, Carol M. Forsblom, Erkka Valo, Valma Harjutsalo, Eoin Patrick Brennan, , Per‐Henrik Groop

Diabetologia · Jun 28, 2022Peer-reviewedGenetic & Genomic Medicine

Assessment of differentially methylated loci in individuals with end-stage kidney disease attributed to diabetic kidney disease

Laura Jane Smyth, Jill Kilner, Viji Nair, Hengxi Liu, Eoin Patrick Brennan, Katie Kerr, Niina Sandholm, Joanne B. Cole, Emma H. Dahlström, Anna Syreeni, Rany M. Salem, Robert G. Nelson, Helen C. Looker, Christopher Wooster, Kerry Anderson, , Amy Jayne McKnight

The paper identifies differentially methylated loci in individuals with end-stage kidney disease due to diabetic kidney disease, linking them to key pathways and genes.

Clinical Epigenetics · May 1, 2021Peer-reviewedMolecular Biology

Genome-wide association study of diabetic kidney disease highlights biology involved in renal basement membrane collagen

Rany M. Salem, Jennifer N. Todd, Niina Sandholm, Joanne B. Cole, Wei‐Min Chen, Darrel Andrews, Marcus G. Pezzolesi, Paul McKeigue, Linda T. Hiraki, Chengxiang Qiu, Viji Nair, Chen Di Liao, Jing Cao, Erkka Valo, Suna Önengüt-Gümüşcü, , José C. Florez

This study identifies 16 genome-wide significant loci associated with diabetic kidney disease, including a protective variant in the COL4A3 gene.

bioRxiv · Dec 19, 2018 · PreprintGenetics