Kristy Chiang

This study identifies a mechanism by which macrophage-derived IL-27 sustains autoreactive CD8+ T cells in autoimmune hepatitis through a local progenitor-to-effector pipeline.

This study shows autoreactive B cells can initiate spontaneous germinal centers and autoimmunity through antibody-dependent mechanisms, independent of T cell interactions or antigen presentation.

This study shows that endothelial cells with a STINGV154M mutation cause persistent skin inflammation after UVB exposure, linking STING activation to impaired myeloid cell recruitment and delayed inflammation resolution.