BioengineeringNature BiotechnologyPeer-reviewed
Engineered mitochondrial A-to-G editors with enhanced efficiency and targeting scope
Liang Chen, Mengjia Hong, Changming Luan…·Dali Li
This paper develops eTd-mtABEs, engineered mitochondrial A-to-G base editors with enhanced efficiency and targeting scope, enabling efficient generation of mtDNA disease models in rat embryos.
32 citationstop 1%