GeneticseLifePeer-reviewed
Tri-methylation of Histone H3 Lysine 4 Facilitates Gene Expression in Ageing Cells
Cristina Cruz, Monica Della Rosa, Christel Krueger…·Jonathan M. Houseley
This study shows that H3K4me3 is essential for maintaining normal gene expression levels across yeast lifespan, with COMPASS mutations reducing lifespan and causing gene expression defects.