Shannon William Davis

This study shows that disrupting Apc in pituitary stem cells causes adamantinomatous craniopharyngioma (aCP) in mice, independent of β-catenin mutations, and identifies Sox2+ stem cells as the cell of origin.

The paper introduces a copula-based method to model non-linear gene co-expression changes along temporal trajectories in scRNA-seq data, applied to study pituitary development in mice.

This study shows that Nxn deficiency causes pituitary dysmorphology and reduced Wnt signaling in mice, suggesting potential endocrinological evaluations for Robinow syndrome patients.

This study investigates the effects of a Prkra frameshift mutation in mice, showing reduced eIF2 phosphorylation and cerebellar abnormalities linked to dystonia.

This study shows ASH1L regulates neuronal connectivity by modulating BDNF/TrkB signaling through its interaction with PRC2 in human neurons, linking ASH1L mutations to autism pathogenesis.