Adam J Dobson

This study evaluates the auxin-inducible gene expression system (AGES) in Drosophila ageing research, finding it effective for transgene induction but with potential confounding phenotypes.

The paper uses chemotypes derived from FTIR spectroscopy and machine learning to predict biological variation and stress response in Drosophila melanogaster.

The paper investigates how reduced insulin signalling affects lifespan and fecundity in Drosophila, showing that mito-nuclear epistasis determines whether the effects are beneficial or detrimental.

This study shows Drosophila and their gut bacteria exchange pantothenate for nitrogen, reprogramming fly metabolism and supporting bacterial growth.

The paper shows that gut microbiota in Drosophila affect ageing through Acetobacter, Tachykinin, and TkR99D, extending lifespan without reducing fecundity.

The paper shows that reaction norm variation explains inconsistent results in dietary restriction studies and highlights the need for personalized approaches in ageing research.

The paper shows mitonuclear epistasis affects fitness from dietary lipids and amino acids in fruitflies, with a tripartite interaction causing quantitative variation.

This study identifies ETS transcription factors as conserved regulators of longevity across species, showing their roles in modulating lifespan through gene expression programs.

This paper identifies GATA transcription factors that regulate the effects of dietary restriction and TOR signaling on lifespan in Drosophila, showing tissue-specific manipulation can decouple longevity from fitness costs.