Author
The Wistar InstituteORCID 0000-0001-7453-1611Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Bryan S. Manning, Linna Zhu, Brennah Murphy…·Martin P Carroll
This study shows that apoptotic cells promote Tim4+ macrophage differentiation through both direct and indirect signaling pathways involving efferocytosis and IL-4R-STAT6 signaling.
Taito Miyamoto, Yujie Ye, Bryan S. Manning…·Nan Zhang
This study shows chemotherapy induces IL1β-dependent neutrophil recruitment, promoting chemoresistance in metastatic ovarian cancer through NETs and immune modulation.
Gauri Mirji, Sajad Ahmad Bhat, Mohamed E. El Sayed…·Rahul Suresh Shinde
This study identifies hippuric acid as a microbial metabolite that enhances pro-inflammatory responses in macrophages via TLR-MyD88 signaling and lipid remodeling, with implications for infection and inflammation.
Brennah Murphy, Taito Miyamoto, Bryan S. Manning…·Nan Zhang
The paper shows that intraperitoneal administration of β-glucan and IFNγ clears ascites and induces IL27-dependent tumor regression in metastatic ovarian cancer models.