Author

Yulia Nefedova

The Wistar InstituteORCID 0000-0002-5121-9294Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Andrew V. KossenkoviD· 2 shared Brennah MurphyiD· 2 shared Bryan S. ManningiD· 2 shared Kohei HamadaiD· 2 shared Taito MiyamotoiD· 2 shared Alessio UgoliniiD· 1 shared Cindy LiniD· 1 shared Dan T. VogliD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Andrew V. KossenkovORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Chemotherapy Induces an IL1β-dependent Neutrophil Recruitment that Promotes Chemoresistance in Metastatic Ovarian Cancer

Taito Miyamoto, Yujie Ye, Bryan S. Manning, Brennah Murphy, Moeko Minakuchi, Kohei Hamada, Rin Mizuno, Mana Taki, Koji Yamanoi, Ryusuke Murakami, Masaki Mandai, Ying Ye, Jayamanna M. Wickramasinghe, Yulia Nefedova, Andrew V. Kossenkov, Nan Zhang

This study shows chemotherapy induces IL1β-dependent neutrophil recruitment, promoting chemoresistance in metastatic ovarian cancer through NETs and immune modulation.

bioRxiv · Sep 21, 2025 · PreprintImmunology

Neutrophil extracellular traps promote tumor chemoresistance to anthracyclines

Cindy Lin, Sarah E. Herlihy, Marina Li, Hui Deng, Rina Kim, Luca L Bernabei, Matthew J. Rosenwasser, Dmitry I. Gabrilovich, Dan T. Vogl, Yulia Nefedova

This study shows that neutrophil extracellular traps (NETs) contribute to tumor resistance to anthracycline chemotherapy by binding the drugs and protecting cancer cells.

bioRxiv · Nov 7, 2024 · PreprintCancer Biology

Intraperitoneal activation of myeloid cells clears ascites and reveals IL27-dependent regression of metastatic ovarian cancer

Brennah Murphy, Taito Miyamoto, Bryan S. Manning, Gauri Mirji, Alessio Ugolini, Toshitha Kannan, Kohei Hamada, Yanfang Peipei Zhu, Daniel T. Claiborne, Lu Huang, Rugang Zhang, Yulia Nefedova, Andrew V. Kossenkov, Filippo Veglia, Rahul Suresh Shinde, Nan Zhang

The paper shows that intraperitoneal administration of β-glucan and IFNγ clears ascites and induces IL27-dependent tumor regression in metastatic ovarian cancer models.

The Journal of Experimental Medicine · Oct 16, 2024Peer-reviewedImmunology