Author

Yi Ai

Fudan UniversityORCID 0000-0001-7454-9678Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

Hong Lu· 1 shared Jungang ZhouiD· 1 shared Lunqiang Zhao· 1 shared Miaomiao Li· 1 shared Yao YuiD· 1 shared Yongming WangiD· 1 shared Yuting He· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

Hong Lu

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1 paper

Recent·Most cited

BioengineeringMetabolic EngineeringPeer-reviewedJul 31, 2026

Humanization of N-glycan-dependent protein quality control system in Kluyveromyces marxianus promotes glycoprotein secretion

Yi Ai, Yuting He, Lunqiang Zhao…·Yao Yu

The paper enhances glycoprotein secretion in yeast by engineering a human-like protein quality control system, resulting in up to 12-fold increased production of therapeutic glycoproteins.

DOI 10.1016/j.ymben.2026.102519

yeastproteomics

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