Author

Nadia Traficante

The University of MelbourneORCID 0000-0001-7459-8576Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alexander DobroviciD· 2 shared Anna DeFazioiD· 2 shared Australian Ovarian Cancer Study· 2 shared Cassandra J. VandenbergiD· 2 shared David D.L. BowtelliD· 2 shared Elizabeth L. KyraniD· 2 shared Franziska GeissleriD· 2 shared Gayanie RatnayakeiD· 2 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Alexander DobrovicORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 7, 2025

Demethylating agents drive PARP inhibitor resistance in ovarian carcinomas with BRCA1 gene silencing

Ksenija Nesic, Franziska Geissler, Lijun Xu…·Matthew J. Wakefield

This study shows that DNMT1 inhibitors reduce BRCA1 promoter methylation in HGSOC, leading to BRCA1 re-expression and PARP inhibitor resistance.

2 citations

humanDNA methylation

𝕏 PostBluesky

Genetic & Genomic MedicineMolecular CancerPeer-reviewedAug 5, 2024

BRCA1 secondary splice-site mutations drive exon-skipping and PARP inhibitor resistance

Ksenija Nesic, John J. Krais, Yifan Wang…·Lyndal S. Edwards

This study identifies secondary splice-site mutations in BRCA1 that drive exon skipping and PARP inhibitor resistance in ovarian and breast cancer.

36 citationstop 2%

humanbulk RNA-seq

𝕏 PostBluesky

Genetic & Genomic MedicineJournal of Medical GeneticsPeer-reviewedJun 16, 2020

Population based targeted sequencing of 54 candidate genes identifies PALB2 as a susceptibility gene for high grade serous ovarian cancer

Honglin Song, Ed Dicks, Jonathan P. Tyrer…·Paul D.P. Pharoah

53 citationstop 4%

humanwhole-exome sequencing

𝕏 PostBluesky