Author
The University of MelbourneORCID 0000-0002-9762-6127Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Philipp Schenk, Shane M. Devine, Simon A. Cobbold…·David Komander
This study identifies WEHI-092, a USP9X inhibitor, and shows it arrests cancer cells in metaphase, suggesting USP9X inhibitors could be selective mitotic poisons.
Ksenija Nesic, Franziska Geissler, Lijun Xu…·Matthew J. Wakefield
This study shows that DNMT1 inhibitors reduce BRCA1 promoter methylation in HGSOC, leading to BRCA1 re-expression and PARP inhibitor resistance.
Ksenija Nesic, John J. Krais, Yifan Wang…·Lyndal S. Edwards
This study identifies secondary splice-site mutations in BRCA1 that drive exon skipping and PARP inhibitor resistance in ovarian and breast cancer.