Tatiana Soldà

This study identifies a reversible temperature block that captures pre-lysosomal intermediates of ERphagy, showing their formation requires autophagy machinery and reveals their structural features.

This study shows EBV uses ER stress and TMX4 to remodel the nuclear envelope, enabling capsid egress during viral maturation.

This paper develops two allosteric GCase correctors that improve folding and lysosomal function in GD patient fibroblasts, reducing cellular stress and offering potential therapy for GD, PD, and Dementia with Lewy Bodies.

The paper identifies TMX5 as a PDI family member that interacts with ERp44 via disulfide bonds, controlling its ER retention and distribution.