Jinman Fang

This study identifies GLUT1 as a driver of immunotherapy resistance in ESCC by epigenetically suppressing senescence and reveals dietary glucose restriction as a potential strategy to enhance immunotherapy efficacy.

This paper identifies microbial transcriptional reprogramming in tumors that generates tumor-specific epitopes, enhancing immunotherapy safety by enabling targeted T cell responses.

MimicNeoAI identifies microbial epitopes and their tumor neoepitope mimics from sequencing data, revealing highly immunogenic microbial epitopes specific to tumors.