Author

Christian J. Lewis

University of SouthamptonORCID 0000-0001-7533-8645Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

A. Christopher GreeniD· 1 shared Brandon Douglas LawrenceiD· 1 shared Brian O. DiekmaniD· 1 shared Hunter LevisiD· 1 shared Jacob Tyler PolaskiiD· 1 shared James C. IatridisiD· 1 shared James H. Atkins· 1 shared Jason GertziD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

A. Christopher GreenORCID

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2 papers

Recent·Most cited

BioengineeringAging CellPeer-reviewedOct 1, 2026

ZNF865 (BLST) Regulates Back Pain via Cell Senescence and DNA Damage Mechanisms

Christian J. Lewis, Hunter Levis, Jonah Holbrook…·Robby D. Bowles

This study identifies ZNF865 as a regulator of cell senescence and DNA damage in intervertebral discs, showing its role in back pain and potential as a therapeutic target.

DOI 10.1111/acel.70754

humanmouse

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 12, 2021

Cholinergic signalling at the body wall neuromuscular junction couples to distal inhibition of feeding in C. elegans

Patricia G. Izquierdo, Thibana Thisainathan, James H. Atkins…·Vincent M. O'Connor

The paper shows that cholinergic signaling at the body wall neuromuscular junction in C. elegans inhibits feeding by coupling with locomotion control.

2 citations

C. elegansexperimental assay

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