Patricia G. Izquierdo

Organophosphate intoxication in C. elegans reveals a new route to mitigate poisoning through the modulation of determinants responsible for nicotinic acetylcholine receptor function

The paper shows that modulating nicotinic acetylcholine receptor function in C. elegans can mitigate organophosphate poisoning through plasticity-promoting mechanisms.

Confounds of using the unc-58 selection marker highlights the importance of genotyping co-CRISPR genes

The paper demonstrates that using co-CRISPR marker genes in C. elegans can lead to hidden genomic rearrangements that affect gene function, emphasizing the need for sequencing co-CRISPR genes after CRISPR editing.

Cholinergic signalling at the body wall neuromuscular junction couples to distal inhibition of feeding in C. elegans

The paper shows that cholinergic signaling at the body wall neuromuscular junction in C. elegans inhibits feeding by coupling with locomotion control.