Bailey A. Knopf

The paper shows that in female mice, carbohydrate quality affects metabolic and neurological responses to low protein diets, but not in males.

This study shows that lifelong dietary valine restriction improves healthspan and extends lifespan in male mice but not females, with distinct molecular effects in different tissues.

This study shows that ovariectomy in female mice enhances their metabolic response to a low protein diet, aligning it with males, while castration has little effect on males.

This study examines the effects of restricting individual branched-chain amino acids on Alzheimer's disease progression in 3xTg mice, finding sex-specific cognitive and metabolic benefits.

This study shows that ketogenesis is not essential for the metabolic benefits of caloric restriction in mice, as Hmgcs2 deletion does not impair key metabolic adaptations.

This study shows that dietary BCAA restriction mitigates metabolic issues and cellular senescence in mice, with tissue-specific effects observed.