Author

Leann Miles

University of PennsylvaniaORCID 0000-0001-7554-4051Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:Drosophila· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Tsz Y. Lo· 2 shared Yuanquan SongiD· 2 shared Chuxi Wang· 1 shared Dan LiiD· 1 shared Feng LiiD· 1 shared Gareth M. ThomasiD· 1 shared Harun Najib NoristaniiD· 1 shared Jessica I. Goldshteyn· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Tsz Y. Lo

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 2, 2025

TBCK-deficiency leads to compartment-specific mRNA and lysosomal trafficking defects in patient-derived neurons

Marco Flores‐Méndez, Jesus A Tintos-Hernández, Leonardo Ramos-Rodriguez…·Xilma Rosa Ortiz-Gonzalez

This study identifies TBCK's role in mRNA and lysosomal trafficking in neurons, showing that TBCK deficiency causes compartment-specific trafficking defects contributing to neurodegeneration.

2 citations

humanproteomics

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NeuroscienceNature CommunicationsPeer-reviewedJun 22, 2021

The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation

Feng Li, Tsz Y. Lo, Leann Miles…·Yuanquan Song

This study identifies the Piezo-Atr-Chek1-Cdc25 pathway as an inhibitory mechanism for axon regeneration, showing that disrupting it enhances regeneration in Drosophila and mammals.

55 citations

Drosophilamouse

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