Yuanquan Song

This study uses long-read sequencing to analyze haplotypes and CAA interruptions in ATXN2 CAG repeats, finding ethnicity-specific and ALS-specific associations.

The paper identifies novel oncogenic gene fusions in fusion-negative gliomas using long-read sequencing and functional validation in Drosophila.

This study identifies a pathway involving Rtca, Rab10, and Itgb1 that regulates Piezo localization and function, promoting axon regeneration inhibition in Drosophila and mice.

This study identifies TBCK's role in mRNA and lysosomal trafficking in neurons, showing that TBCK deficiency causes compartment-specific trafficking defects contributing to neurodegeneration.

This study identifies the Piezo-Atr-Chek1-Cdc25 pathway as an inhibitory mechanism for axon regeneration, showing that disrupting it enhances regeneration in Drosophila and mammals.

The paper identifies pathogenic variants in SMARCA5 as a cause of a neurodevelopmental syndrome with mild facial dysmorphia and developmental delay.

The paper identifies ISWI as a chromatin remodeler required for adult sleep in Drosophila, with distinct developmental roles in sleep and other behaviors.

This study uses optogenetics to activate ERK and AKT signaling in Drosophila, enhancing axon regeneration and functional recovery in both PNS and CNS.