Author

Tsz Y. Lo

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:Drosophila· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Leann MilesiD· 2 shared Yuanquan SongiD· 2 shared Chuxi Wang· 1 shared Dan LiiD· 1 shared Feng LiiD· 1 shared Gareth M. ThomasiD· 1 shared Harun Najib NoristaniiD· 1 shared Jessica I. Goldshteyn· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Leann MilesORCID

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2 papers

Recent·Most cited

TBCK-deficiency leads to compartment-specific mRNA and lysosomal trafficking defects in patient-derived neurons

Marco Flores‐Méndez, Jesus A Tintos-Hernández, Leonardo Ramos-Rodriguez, Leann Miles, Tsz Y. Lo, Yuanquan Song, Xilma Rosa Ortiz-Gonzalez

This study identifies TBCK's role in mRNA and lysosomal trafficking in neurons, showing that TBCK deficiency causes compartment-specific trafficking defects contributing to neurodegeneration.

bioRxiv · Mar 2, 2025 · PreprintNeuroscience

The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation

Feng Li, Tsz Y. Lo, Leann Miles, Qin Wang, Harun Najib Noristani, Dan Li, Jingwen Niu, Shannon Trombley, Jessica I. Goldshteyn, Chuxi Wang, Shuchao Wang, Jingyun Qiu, Katarzyna Pogoda, Kalpana Mandal, Megan Brewster, , Yuanquan Song

This study identifies the Piezo-Atr-Chek1-Cdc25 pathway as an inhibitory mechanism for axon regeneration, showing that disrupting it enhances regeneration in Drosophila and mammals.

Nature Communications · Jun 22, 2021Peer-reviewedNeuroscience