Author

Annika Jeschke

German Cancer Research Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Thomas G. P. GrünewaldiD· 2 shared Alina Ritter· 1 shared Ana BanitoiD· 1 shared Angeline Praveena Enton Raj· 1 shared Annelies Van HemelrykiD· 1 shared Bram De WildeiD· 1 shared David Obermeier· 1 shared Ellen SandersiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Thomas G. P. GrünewaldORCID

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2 papers

Recent·Most cited

Targeting replication stress in neuroblastoma by exploiting the synergistic potential of second generation RRM2 and CHK1 inhibitors

Iris H. Nelen, Soetkin Leys, Sarah-Lee Bekaert, Fanny De Vloed, Fien Martens, Ellen Sanders, Angeline Praveena Enton Raj, Annika Jeschke, Shunya Ohmura, Thomas G. P. Grünewald, Liselot M. Mus, Tim Lammens, Nadine Van Roy, Bram De Wilde, Frank Speleman, , Kaat Durinck

This study identifies synergistic effects of second-generation RRM2 and CHK1 inhibitors in neuroblastoma and sarcomas, showing enhanced replication stress and apoptosis.

Cell Death and Disease · Feb 25, 2026Peer-reviewedCancer Biology

Targeting CXADR-mediated AKT signaling suppresses tumorigenesis and enhances chemotherapy efficacy in Ewing sarcoma

Alina Ritter, Malenka Zimmermann, Florian H. Geyer, Pablo Táboas, David Obermeier, Martha J. Carreño Gonzalez, Kimberley M. Hanssen, Tobias Faehling, Jana Siebenlist, Annika Jeschke, Laura Romero‐Pérez, Roland Imle, Ana Banito, Enrique de Álava, Wolfgang Hartmann, , Florencia Cidre‐Aranaz

This study identifies CXADR as a driver of Ewing sarcoma metastasis and shows that targeting AKT signaling with Capivasertib enhances chemotherapy efficacy in CXADR-high tumors.

bioRxiv · Aug 7, 2025 · PreprintCancer Biology