Author

Basil T. Thommen

Swiss Tropical and Public Health InstituteORCID 0000-0001-7655-2440Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Cell Biology· 1 Genetics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:plant (other)· 4 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Nicolas M. B. BrancucciiD· 4 shared Armin PasseckeriD· 3 shared Christin GumppiD· 3 shared Matthias RottmanniD· 3 shared Till Steffen VossiD· 3 shared Christof GrüringiD· 2 shared Alexander SchmidtiD· 1 shared Amr Hamed Mahmoud· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersMolecular Biology

Nicolas M. B. BrancucciORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 13, 2026

A high-throughput compound screen identifies multiple druggable targets in Plasmodium falciparum transmission stages

Leonie Seefeldt, Christin Gumpp, Olivia Carril…·Nicolas M. B. Brancucci

This study identifies three druggable targets in Plasmodium falciparum gametocytes using high-throughput screening and reveals resistance mechanisms for one compound.

DOI 10.64898/2026.09.10.747198

plant (other)experimental assay

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GeneticsbioRxivPreprintJun 10, 2026

Duplication of superoxide dismutase and a mutation in aquaglyceroporin mediates the sensitivity of Plasmodium falciparum to cryptosporin, a natural product derived from Acaromyces ingoldii

Tiantian Jiang, Jennifer E. Collins, Jin Woo Lee…·Elizabeth A. Winzeler

This study identifies a mutation in PfAQP and duplication of superoxide dismutase genes as mechanisms of resistance to cryptosporin in Plasmodium falciparum.

DOI 10.64898/2026.06.08.730986

plant (other)statistical model

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MicrobiologyNature CommunicationsPeer-reviewedJul 25, 2025

An all-in-one pipeline for the in vitro discovery and in vivo testing of Plasmodium falciparum malaria transmission blocking drugs

Nicolas M. B. Brancucci, Christin Gumpp, Geert‐Jan van Gemert…·Till Steffen Voss

The paper develops an in vitro and in vivo platform for testing malaria transmission-blocking drugs using engineered Plasmodium falciparum gametocytes and humanized mice.

8 citationstop 3%

humanmouse

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Cell BiologymSpherePeer-reviewedSep 5, 2024

The three Plasmodium falciparum Aurora-related kinases display distinct temporal and spatial associations with mitotic structures in asexual blood stage parasites and gametocytes

Matthias Wyss, Basil T. Thommen, Jacob Kofler…·Till Steffen Voss

The paper investigates the spatiotemporal roles of three Aurora-related kinases in Plasmodium falciparum mitosis and gametogenesis, revealing distinct functions in cell division processes.

8 citations

plant (other)experimental assay

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Molecular BiologyeLifePeer-reviewedNov 7, 2023

Genetic validation of PfFKBP35 as an antimalarial drug target

Basil T. Thommen, Jerzy Michal Dziekan, Fiona Achcar…·Nicolas M. B. Brancucci

This study genetically validates PfFKBP35 as a lethal target in Plasmodium falciparum, showing its role in ribosome homeostasis and revealing non-canonical modes of action for FK506.

5 citations

humanexperimental assay

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