Author
Walter and Eliza Hall Institute of Medical ResearchORCID 0000-0002-5277-0395Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Samuel Pažický, Jerzy Michal Dziekan, Seth Tjia…·Zbynek Bozdech
The paper identifies new drug targets in Plasmodium falciparum using thermal proteome profiling combined with molecular docking and MS-CETSA.
Paola Favuzza, Madeline G. Dans, Wenyin Su…·Alan F. Cowman
This study evaluates resistance development to PMX-selective and dual PMIX/X inhibitors in Plasmodium falciparum, finding that dual inhibitors have a higher resistance barrier.
Wenyin Su, William Nguyen, Ghizal Siddiqui…·Madeline G. Dans
This study investigates the on-target activity of plasmepsin V peptidomimetics in Plasmodium falciparum by combining chemoproteomic methods and genetic validation.
Basil T. Thommen, Jerzy Michal Dziekan, Fiona Achcar…·Nicolas M. B. Brancucci
This study genetically validates PfFKBP35 as a lethal target in Plasmodium falciparum, showing its role in ribosome homeostasis and revealing non-canonical modes of action for FK506.