Nicolas M. B. Brancucci

This study identifies three druggable targets in Plasmodium falciparum gametocytes using high-throughput screening and reveals resistance mechanisms for one compound.

The paper introduces a high-throughput in vitro assay for evaluating antimalarial drug combinations and their pharmacodynamic interactions, showing improved efficiency and resolution compared to existing methods.

The paper develops an in vitro and in vivo platform for testing malaria transmission-blocking drugs using engineered Plasmodium falciparum gametocytes and humanized mice.

The paper investigates the spatiotemporal roles of three Aurora-related kinases in Plasmodium falciparum mitosis and gametogenesis, revealing distinct functions in cell division processes.

This study genetically validates PfFKBP35 as a lethal target in Plasmodium falciparum, showing its role in ribosome homeostasis and revealing non-canonical modes of action for FK506.

The paper introduces ILRA, a tool that improves long read assemblies by correcting homopolymer errors and merging contigs, resulting in higher-quality genome assemblies.