Lev Y. Yampolsky

The paper shows that circulating hemocytes in Daphnia continue to proliferate throughout their lifespan without evidence of a dedicated hemopoietic stem cell population.

The paper analyzes single-nuclei transcriptomes of Daphnia magna to study aging and reproductive rejuvenation, identifying age-related and reproductive changes in cell type abundance and transcriptional patterns.

The paper presents the first single-cell transcriptomic atlas of Daphnia magna, identifying over 30 cell types and providing insights into their functional roles and potential ecological adaptations.

The paper tests if BHB or NMN can mimic caloric restriction in Daphnia, finding BHB reduces early mortality similar to CR, while NMN does not and may negate BHB's effects.

This study examines DNA methylation in Daphnia magna and finds no significant age-related changes in methylation patterns.

This study shows that b-hydroxybutyrate reduces lifespan but increases fecundity in Daphnia magna, with a transgenerational effect dependent on genotype.

The paper analyzes RNAseq data from Daphnia magna to show that post-senescence reproductive events involve reversal of age-related transcriptional changes, suggesting potential mechanisms for reproductive rejuvenation.

This study examines baseline longevity of Daphnia magna clones under various conditions, finding strong genotype-by-environment interactions and differences in lifespan extension responses to caloric restriction.

The paper investigates maternal age effects on offspring longevity and male production in Daphnia magna, finding a reverse Lansing effect and linking it to lipid provisioning and mitochondrial quality.

The paper shows Pou5f3 and Sox19b independently regulate enhancer chromatin accessibility, affecting zygotic gene expression in zebrafish embryos.

This study uses quantitative proteomics to analyze protein expression changes across life phases of Daphnia pulex, revealing functional shifts in response to environmental stress.

The paper investigates how Pou5f3, SoxB1, and Nanog influence chromatin remodeling at High Nucleosome Affinity Regions during Zygotic Genome Activation in zebrafish.