Author

Morad C. Malek

Vanderbilt UniversityORCID 0000-0002-6796-1899Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Developmental Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Adel EskarosiD· 1 shared Alvin C. PowersiD· 1 shared Andrea AscuraiD· 1 shared Andrew F. Livingston· 1 shared Angela R.S. KruseiD· 1 shared Claire F. ScottiD· 1 shared Cody R. MarshalliD· 1 shared Cora E. AndersoniD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperSystems Biology

Adel EskarosORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Early Host-Virus RNA Interactions Reveal SPEN-Driven m6A Regulation as a Major Determinant of Henipavirus Infection

Andrea Ascura, Stephen Clarke, Andrew F. Livingston, Jackson B. Trotman, Sander Haigh, Morad C. Malek, J. Mauro Calabrese, Manuel Ascano

The paper identifies SPEN-driven m6A regulation as a key factor in henipavirus infection by analyzing host-virus RNA interactions using VIR-CLASP.

bioRxiv · Nov 21, 2025 · PreprintBiochemistry

Integrative Spatial Omics for Systems-Level Mapping of Pathological Niches

Angela R.S. Kruse, Roy Lardenoije, Lukasz G. Migas, Claire F. Scott, Cody R. Marshall, Morad C. Malek, Adel Eskaros, Thai H. Pham, Kristie I. Aamodt, Madeline E. Colley, Lissa Ventura‐Antunes, Melissa A. Farrow, Raf Van de Plas, Joana P. Gonçalves, Matthew Schrag, , Jeffrey M. Spraggins

This paper introduces a multimodal pipeline for spatiomolecular analysis of tissue samples, demonstrating its application in Alzheimer's disease and type 2 diabetes.

bioRxiv · Sep 12, 2025 · PreprintSystems Biology

Inverse Lansing effect: maternal age and provisioning affecting daughters' longevity and male offspring production

Cora E. Anderson, Morad C. Malek, Rachael Alice Jonas-Closs, Yongmin Cho, Leonid Peshkin, Marc W. Kirschner, Lev Y. Yampolsky

The paper investigates maternal age effects on offspring longevity and male production in Daphnia magna, finding a reverse Lansing effect and linking it to lipid provisioning and mitochondrial quality.

The American Naturalist · Jun 6, 2022Peer-reviewedDevelopmental Biology