YOUNG PLASMA REJUVENATES BLOOD DNA METHYLATION PROFILE, PROLONGS MEAN LIFESPAN AND IMPROVES HEALTH IN OLD RATS
Priscila Chiavellini, Martina Canatelli-Mallat, Marianne Lehmann, Joseph Alan Zoller, Juozas Gordevičius, Maria D. Gallardo, Diana C. Pasquini, Ezequiel Lacunza, Claudia Beatriz Hereñú, Gustavo R. Morel, Steve Horvath, Rodolfo G. Goya
This study shows that young rat plasma reduces DNA methylation age, extends lifespan, and improves health in old rats.
bioRxiv · Dec 1, 2022 · PreprintBioinformatics