COGNITIVE REJUVENATION IN OLD RATS BY HIPPOCAMPAL OSKM GENE THERAPY
Steve Horvath, Ezequiel Lacunza, Martina Canatelli-Mallat…·Rodolfo G. Goya
This study shows that OSKM gene therapy in old rats improves spatial learning and memory, reduces epigenetic age, and reverses age-related DNA methylation changes in the hippocampus.