Yehuda Tzfati

The paper shows that human-length telomeres in mice restrict hematopoietic stem cell regenerative potential under stress conditions.

This study introduces two RTEL1 mouse models with distinct mutations at amino acid 492, showing that M492K affects telomere length while M492I impairs telomere protection, leading to different disease phenotypes.

This study models DDR syndromes in killifish and shows that cGAS-STING pathway activation contributes to disease phenotypes, with cGAS mutation partially rescuing defects.

This paper introduces a mouse model with human-length telomeres by modifying RTEL1 and shows its impact on regenerative capacity.