Author

Liam Clayfield

Cancer Research UK Manchester InstituteORCID 0000-0001-7750-5080Unclaimed ORCID profile · follow to get notified of new preprints

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Cancer Biology· 1

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Duncan L. SmithiD· 1 shared Eve LeddyiD· 1 shared Georges LacaudiD· 1 shared Jessica WhittleiD· 1 shared Jingru XuiD· 1 shared Michael Lie‐A‐LingiD· 1 shared Özgen DeniziD· 1 shared Robert SellersiD· 1 shared

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2025-2025 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Duncan L. SmithORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintNov 12, 2025

Epigenetic silencing of transposable elements by IRF2BP2 is a selective dependency of myeloid leukemia

Jingru Xu, Jessica Whittle, Liam Clayfield…·Georges Lacaud

This study identifies IRF2BP2 as a critical regulator of transposable element silencing in AML, showing its loss leads to TE activation and leukemia cell death.

DOI 10.1101/2025.11.12.688028

humanscRNA-seq

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