MicrobiologyAntimicrobial Agents and ChemotherapyPeer-reviewed
The Spx stress regulator confers high-level β-lactam resistance and decreases susceptibility to last-line antibiotics in methicillin resistant Staphylococcus aureus
Tobias K. Nielsen, Ida Birkjær Petersen, Lijuan Xu…·Dorte Frees
This study identifies Spx as a stress regulator that enhances β-lactam resistance and reduces susceptibility to last-line antibiotics in MRSA through a redox-independent mechanism.