Author

Xue Xiao

The University of Texas Southwestern Medical CenterORCID 0000-0001-7820-6920Unclaimed ORCID profile · follow to get notified of new preprints

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Xue Xiao1 paper · The University of Texas Southwestern Medical Center

Biology Disciplines

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:graph neural network· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Bo Zeng· 1 shared Ce WangiD· 1 shared Chen Tang· 1 shared Guanghua XiaoiD· 1 shared Guoling HuangiD· 1 shared Heping Wang· 1 shared Jiaqi Wu· 1 shared Lei DongiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Bo Zeng

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 16, 2026

Myeloid DC-SIGN drives tumor immune evasion and resistance to PD-1 blockade through ICAM-2-ERM-mediated T-cell mechanosuppression

Ting Pan, T Z Wang, Jiaqi Wu…·Ce Wang

This study identifies DC-SIGN as a mechanosuppressive checkpoint that drives tumor immune evasion and resistance to PD-1 blockade by suppressing T-cell function through ICAM-2-ERM signaling.

DOI 10.64898/2026.01.19.699861

𝕏 PostBluesky

BioinformaticsBriefings in BioinformaticsPeer-reviewedJan 1, 2026

3D reconstruction of spatial transcriptomics with spatial pattern enhanced graph convolutional neural network

Chen Tang, Yuansheng Zhou, Xue Xiao…·Lori Xu

This paper introduces Spa3D, a method that reconstructs 3D spatial structures from 2D spatial transcriptomics data, improving spatial domain identification, cell-cell communication analysis, and developmental trajectory modeling.

1 citation

spatial transcriptomicsdeep learning

𝕏 PostBluesky