Author
Synthego (United States)ORCID 0000-0001-7824-0950Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Brent D. Aulston, Kirstan Gimse, Hannah Bazick…·Subhojit Roy
The paper uses CRISPR-Cas9 to edit the App gene in mice, reducing Alzheimer's disease symptoms and showing long-term benefits.
Irene P. Chen, James E. Longbotham, Sarah McMahon…·Mélanie Ott
The paper shows that BET proteins are antiviral factors against SARS-CoV-2, and the viral E protein neutralizes BET-mediated post-entry antiviral effects.
Jichao Sun, Jared Carlson-Stevermer, Utpal Das…·Subhojit Roy
This paper introduces a CRISPR/Cas9 strategy to edit APP and manipulate the amyloid pathway in Alzheimer's disease by reducing β-cleavage and Aβ while increasing α-cleavage.
Jared Carlson-Stevermer, Ty Harkness, Ryan Prestil…·Krishanu Saha
This study develops micropatterned substrates to monitor reprogramming of human somatic cells, identifying nuclear features that distinguish fully from partially reprogrammed cells.