Author

Jichao Sun

Jinan UniversityORCID 0000-0002-7671-2157Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Organism:human· 1

Frequent Co-Authors

Jared Carlson-StevermeriD· 2 shared Krishanu SahaiD· 2 shared Subhojit RoyiD· 2 shared Amanda M. Snead· 1 shared Andrew A. SprouliD· 1 shared Andrew J. PeterseniD· 1 shared Anita BhattacharyyaiD· 1 shared Anjon AudhyaiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Jared Carlson-StevermerORCID

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2 papers

Recent·Most cited

Long term rescue of Alzheimer deficits in vivo by one-time gene-editing of App C-terminus.

Brent D. Aulston, Kirstan Gimse, Hannah Bazick, Enikö A. Kramár, Donald P. Pizzo, Farbod Shavarebi, Trinity Rust, Sheila Garcia Rosa, Leonardo A Parra‐Rivas, Jichao Sun, Kristen Branes‐Guerrero, Nidhi Checka, Neda Bagheri, Sara B. Rosenthal, Nihal Satyadev, , Subhojit Roy

The paper uses CRISPR-Cas9 to edit the App gene in mice, reducing Alzheimer's disease symptoms and showing long-term benefits.

bioRxiv · Jun 8, 2024 · PreprintNeuroscience

A CRISPR/Cas9 based strategy to manipulate the Alzheimer’s amyloid pathway

Jichao Sun, Jared Carlson-Stevermer, Utpal Das, Minjie Shen, Marion Delenclos, Amanda M. Snead, Lina Wang, Jonathan Loi, Andrew J. Petersen, Michael E. Stockton, Anita Bhattacharyya, Mathew V. Jones, Andrew A. Sproul, Pamela J. McLean, Xinyu Zhao, , Subhojit Roy

This paper introduces a CRISPR/Cas9 strategy to edit APP and manipulate the amyloid pathway in Alzheimer's disease by reducing β-cleavage and Aβ while increasing α-cleavage.

bioRxiv · Apr 28, 2018 · PreprintNeuroscience