Author

Safia El Jailani

Centre National de la Recherche ScientifiqueORCID 0009-0004-4604-9915Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

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Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Assay:proteomics· 1

Frequent Co-Authors

Damien CladièreiD· 2 shared Eulalie BuffiniD· 2 shared Katja WassmanniD· 2 shared Sandra A. TouatiiD· 2 shared Alberto M. PendásiD· 1 shared Andrea MusacchioiD· 1 shared Arianna Esposito-VerzaiD· 1 shared Christophe RacheziD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCell Biology

Damien CladièreORCID

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2 papers

Recent·Most cited

Set mediates chromosome alignment and Cohesin cleavage independently of direct PP2A-B56-binding in oocyte meiosis

Leonor Keating, Arianna Esposito-Verza, Warif El Yakoubi, Yulia Gryaznova, Safia El Jailani, Damien Cladière, Sandra A. Touati, Eulalie Buffin, Christophe Rachez, Varvara Sarli, Alberto M. Pendás, Wei Gu, Andrea Musacchio, Katja Wassmann

This study shows Set is essential for chromosome alignment and Cohesin cleavage in oocyte meiosis, functioning through Aurora B regulation and chromatin environment modulation, independent of PP2A-B56 interaction.

bioRxiv · Aug 21, 2026 · PreprintCell Biology

Elimination of separase inhibition reveals absence of cohesin protection in oocyte metaphase II

Safia El Jailani, Damien Cladière, Elvira Nikalayevich, Sandra A. Touati, Vera Chesnokova, Shlomo K. Melmed, Eulalie Buffin, Katja Wassmann

This study investigates separase inhibition and cohesin protection in oocytes, finding that cohesin is not protected early in meiosis I and at metaphase II arrest, and that kinetochore individualization in meiosis I is required for cohesin cleavage in meiosis II.

bioRxiv · Feb 11, 2025 · PreprintCell Biology