Author

Hiroaki Ohishi

Kyushu UniversityORCID 0000-0001-6672-4093Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Hiroshi OchiaiiD· 4 shared Satoshi UchinoiD· 3 shared Yasuyuki OhkawaiD· 3 shared Hiroshi KimurâiD· 2 shared Hitoshi OwadaiD· 2 shared Takashi YamamotoiD· 2 shared Takeru FujiiiD· 2 shared Xiaohui Gao· 2 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersMolecular Biology

Hiroshi OchiaiORCID

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4 papers

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 10, 2026

Minute-scale coupling of chromatin marks and transcriptional bursts

Xiaohui Gao, Chaebeen Ko, Yuanchao Dong…·Hiroshi Ochiai

The paper shows that chromatin modifications around genes fluctuate with transcriptional activity in mouse embryonic stem cells, revealing minute-scale coupling between histone marks and transcriptional bursts.

DOI 10.64898/2026.02.08.704500

mouseChIP-seq

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Molecular BiologybioRxivPreprintSep 10, 2024

RNA-mediated SOX2 temporal dynamics govern dual chromatin engagement modes at Nanog

Bitong Li, Yew Yan Wong, Yoshiaki Kobayashi…·Mathias François

The paper uses single-molecule imaging to show RNA fluctuations modulate SOX2 dynamics at the Nanog locus, revealing RNA-dependent feedback in transcriptional regulation.

1 citation

humanimaging

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Molecular BiologybioRxivPreprintNov 27, 2023

Transcription-coupled changes in higher-order genomic structure and transcription hub viscosity prolong enhancer-promoter connectivity

Hiroaki Ohishi, Soya Shinkai, Hitoshi Owada…·Hiroshi Ochiai

The paper examines enhancer-promoter interactions in mouse embryonic stem cells, finding that transcriptional activity increases genomic viscosity, stabilizing these interactions.

6 citations

mousebulk RNA-seq

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Molecular BiologyNature CommunicationsPeer-reviewedDec 20, 2022

STREAMING-tag system reveals spatiotemporal relationships between transcriptional regulatory factors and transcriptional activity

Hiroaki Ohishi, Seiru Shimada, Satoshi Uchino…·Hiroshi Ochiai

The paper develops a STREAMING-tag system to study spatiotemporal relationships between transcriptional factors and activity in living cells.

40 citations

mouseexperimental assay

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