Author

Georg Tascher

Goethe University FrankfurtORCID 0000-0002-5907-3947Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Christian MünchiD· 2 shared Denisa BojkováiD· 1 shared Gina GotthardtiD· 1 shared Giulio FerrarioiD· 1 shared Hannah J. UckelmanniD· 1 shared Janik WeckesseriD· 1 shared Jindrich Jr. CinatliD· 1 shared José Pedro Friedmann AngeliiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Christian MünchORCID

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2 papers

Recent·Most cited

The cysteine-reactive covalent RNF4 ligand CCW16 induces ferroptosis in AML cells by activation of ROS signaling

Gina Gotthardt, Janik Weckesser, Georg Tascher, Sara Barros da Gama, Hannah J. Uckelmann, Shibo Sun, Martin P. Schwalm, Thorsten Mosler, Giulio Ferrario, José Pedro Friedmann Angeli, Christian Münch, Stefan Knapp, Stefan P Müller

This study shows that the RNF4 ligand CCW16 induces ferroptosis in AML cells through a RNF4-independent mechanism by causing covalent protein modifications and upregulating ferroptosis markers.

EMBO Reports · Oct 16, 2025Peer-reviewedCell Biology

Growth factor receptor signaling inhibition prevents SARS-CoV-2 replication

Kevin Klann, Denisa Bojková, Georg Tascher, Sandra Ciesek, Christian Münch, Jindrich Jr. Cinatl

This study identifies growth factor receptor signaling as a key pathway for SARS-CoV-2 replication and shows that inhibiting it prevents viral replication in human cells.

Molecular Cell · Aug 11, 2020Peer-reviewedSystems Biology