Lola Boutin

The paper uses spatial transcriptomics to analyze immune infiltration in pediatric ependymoma, revealing compartmentalized immune niches and heterogeneous T-cell therapy opportunities.

This study shows ALK R1275Q mutation sustains an immature SCP-like cell state during sympathoadrenal commitment, increasing susceptibility to MYCN-driven neuroblastoma initiation.

This study shows that combining palbociclib and crizotinib enhances senescence and immune recognition in melanoma cells regardless of BRAF/NRAS status, reducing tumor growth.

This study shows that γδT cells can selectively kill medulloblastoma cells without harming neurons or stem cells, offering a safer and more effective treatment option.

This paper develops a zebrafish model for medulloblastoma drug testing, showing that neural stem cell culture conditions enhance tumor cell homing and aggressiveness, enabling high-throughput screening.