Rudi D’Hooge

This study shows TMEM55B and TMEM55A regulate lysosome distribution in neurons by affecting motor protein transport, with TMEM55B specifically promoting anterograde transport of LAMP1-positive organelles.

The paper investigates the interaction between oxytocin and dopamine in social safety learning in mice using the social transmission of food preference paradigm, finding that oxytocin enhances learning only when dopamine signaling is intact.

This study shows that oxytocin enhances trust acquisition in male mice but blocks trust violation learning, while its antagonist has similar effects, with no impact on females.

This paper shows that lack of the glycine receptor alpha 2 in mice increases striatal activity and motivated behavior, linking it to psychiatric disorders like schizophrenia and addiction.

The paper shows that astrocyte calcium dysfunction leads to early network hyperactivity in Alzheimer's Disease, which can be reversed by restoring calcium signaling.

This study shows scopolamine prevents context-dependent reinstatement of fear in rats after aversive experiences.

This study identifies miR-132 deficiency as a cause of impaired adult hippocampal neurogenesis in Alzheimer's disease and shows that restoring miR-132 levels can reverse these deficits and memory issues.

This study examines how social isolation during adolescence affects socio-cognitive behaviors in APP/PS1 mice, revealing context-dependent impacts on memory and social recognition.

The paper examines the effects of social isolation on Alzheimer’s Disease phenotype in aged APP KI mice, finding mixed results with some behavioral differences emerging after isolation.

This study shows that CYFIP1 haploinsufficiency in mice causes reduced brain functional connectivity and white matter defects, linking it to neuropsychiatric disorders like Autism and Schizophrenia.