Jin J. Zhou

This study identifies genetic loci associated with diabetic peripheral neuropathy, implicating serine biosynthesis in disease susceptibility through convergent evidence from common and rare variants.

This paper corrects collider bias in a GWAS of diabetes-related heart failure, identifying novel loci and showing bidirectional genetic associations between T2D and HF.

This paper introduces a penalized regression algorithm for multivariate GWAS using iterative hard thresholding, showing improved efficiency and reduced false positives compared to existing methods.

The paper identifies four genetic loci associated with risk across seven cardiometabolic traits using GWAS in the UK Biobank and replication in independent meta-analyses.

Multi-ethnic type 2 diabetes (T2D) meta-analysis of 228,499 cases and 1,178,783 controls finds 318 previously unreported loci, 804 expression-colocalized genes, and 13 SNP-by-T2D vascular-outcome interactions.

This paper introduces an improved iterative hard thresholding method for GWAS that enhances true positive rates and reduces false positives compared to traditional approaches.

The paper investigates the genetic relationship between low LDL-C and type-2 diabetes, identifying 31 loci and suggesting a causal link through Mendelian randomization.

The paper develops exact tests for variance components in longitudinal microbiome studies and applies them to HIV-infected patients, identifying associations between lung microbiome genera and lung function.