Author

Magali Dhellemmes

Centre National de la Recherche ScientifiqueORCID 0000-0001-7983-3221Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:differential expression· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Aitana Perea-GómeziD· 2 shared Furong TangiD· 2 shared Marie‐Christine ChaboissieriD· 2 shared Natividad Bellido-CarrerasiD· 2 shared Aurelie Despoux· 1 shared Aurélie LardenoisiD· 1 shared Caroline CaziniD· 1 shared Charles CouttoniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersDevelopmental Biology

Aitana Perea-GómezORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Rspo1 dependent WNT signaling safeguards ovarian development by suppressing androgen signaling

Furong Tang, Natividad Bellido-Carreras, Kheira Bouzid, Aurélie Lardenois, Thomas Darde, Magali Dhellemmes, Aurelie Despoux, Mirko Peitzsch, Marie‐Christine Birling, Frédéric Chalmel, Marie‐Christine Chaboissier, Aitana Perea-Gómez

This study shows RSPO1/WNT/B-catenin signaling suppresses androgen signaling during ovarian development in mice, with androgen receptor inhibition rescuing development in mutants.

bioRxiv · Sep 23, 2026 · PreprintDevelopmental Biology

NR2F2 is required in the embryonic testis for Fetal Leydig Cell development

Aitana Perea-Gómez, Natividad Bellido-Carreras, Magali Dhellemmes, Furong Tang, Coralie Le Gallo, Marie‐Christine Chaboissier

This study shows NR2F2 is essential for fetal Leydig cell development in mouse testes and links it to 46, XY DSD associated with NR2F2 variants.

eLife · Jul 10, 2025Peer-reviewedDevelopmental Biology

Oligogenic heterozygous inheritance of sperm abnormalities in mouse

Guillaume Martinez, Charles Coutton, Corinne Loeuillet, Caroline Cazin, Jana Muroňová, Magalie Boguenet, Emeline Lambert, Magali Dhellemmes, Geneviève Chevalier, Jean‐Pascal Hograindleur, Charline Vilpreux, Yasmine Neirijnck, Zine‐Eddine Kherraf, Jessica Escoffier, Serge Nef, , Christophe Arnoult

The paper investigates oligogenic inheritance of sperm abnormalities in mice, finding that increasing numbers of heterozygous mutations worsen sperm morphology and motility.

eLife · Apr 22, 2022Peer-reviewedGenetics