José Andrés Fernández

Muscle spatial lipidomics identifies early ALS signatures in presymptomatic SOD1G93A mice

The paper identifies early ALS-related lipid changes in presymptomatic SOD1G93A mice using lipid imaging mass spectrometry, showing sex-dependent and fiber-type-specific alterations detectable before symptoms.

A Fine-Tuned Phosphatidylinositol Profile Contributes to Colonocyte Differentiation and Malignization: Evidence From Integrated Omics

The paper integrates transcriptomic and lipidomic data to identify gene regulatory networks involved in colonocyte differentiation and their disruption in colon cancer.

Characterization of the Lipidome of Neurons in Mouse Brain Nuclei using Imaging Mass Spectrometry

This study characterizes the lipidome of specific neuronal populations in mouse brain nuclei using imaging mass spectrometry, revealing sex-based differences in lipid profiles.

IRF5 regulates microglial myelin clearance and cholesterol metabolism after demyelination

This study shows that IRF5 regulates microglial myelin clearance and cholesterol metabolism after demyelination, with implications for remyelination in multiple sclerosis.