Author

Zihui Zhang

Stanford UniversityORCID 0000-0001-8002-9396Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Zihui Zhang1 paper · Zhejiang University

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Gavin C. TouponseiD· 3 shared Matthew B. PomrenzeiD· 3 shared Neir EsheliD· 3 shared Robert C. MalenkaiD· 3 shared Amei N. Shank· 2 shared Nicholas DenommeiD· 2 shared Teema YassineiD· 2 shared Allen P. F. CheniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersNeuroscience

Gavin C. TouponseORCID

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3 papers

Recent·Most cited

Local control of dopamine release in nucleus accumbens gates opioid withdrawal aversion

Matthew B. Pomrenze, Jason Tucciarone, Gavin C. Touponse, Nicholas Denomme, BaDoi N. Phan, Robyn St. Laurent, Julia A Galiza Soares, Daniel F. Cardozo Pinto, Michaela Y. Guo, Jinhee Baek, Allen P. F. Chen, Zihui Zhang, Amei N. Shank, Zachary Freyberg, Andreas R. Pfenning, , Robert C. Malenka

The paper identifies Tshz1 neurons in the nucleus accumbens as critical for withdrawal aversion by modulating dopamine release and mGluR8 activity, offering a new therapeutic target for opioid use disorder.

bioRxiv · May 28, 2026 · PreprintNeuroscience

Serotonin modulates nucleus accumbens circuits to suppress aggression

Zihui Zhang, Gavin C. Touponse, Pia J. Alderman, Teema Yassine, Matthew B. Pomrenze, Troy W. Harris, Amei N. Shank, Robert C. Malenka, Neir Eshel

This study identifies a mechanism by which serotonin suppresses aggression by modulating nucleus accumbens circuits in mice.

bioRxiv · Nov 26, 2025 · PreprintNeuroscience

Cholinergic modulation of dopamine release drives effortful behavior

Gavin C. Touponse, Matthew B. Pomrenze, Teema Yassine, Viraj Mehta, Nicholas Denomme, Zihui Zhang, Robert C. Malenka, Neir Eshel

The paper shows that cholinergic modulation of dopamine release enhances effortful behavior by amplifying dopamine responses to high-effort rewards.

bioRxiv · Jun 18, 2025 · PreprintNeuroscience