Author

Humaira Ilyas

Albert Einstein College of MedicineORCID 0000-0002-5784-9086Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandra SchureriD· 1 shared Benjamin M. LortoniD· 1 shared Daniel K. BorgeriD· 1 shared David ShechteriD· 1 shared Donald F. HuntiD· 1 shared Ellen AngelesiD· 1 shared Irene Mariam RoyiD· 1 shared Jeffrey ShabanowitziD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexandra SchurerORCID

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1 paper

Recent·Most cited

TTLL4 glutamyltransferase is a therapeutic target for NPM1-mutated acute myeloid leukemia

Alexandra Schurer, Humaira Ilyas, Maxim I. Maron, Subray S. Hegde, Melissa R. Leyden, Irene Mariam Roy, Rotila Hyka, Lucas Dada, Jeffrey Shabanowitz, Donald F. Hunt, Ellen Angeles, Victor Morell, Benjamin M. Lorton, Shira G. Glushakow-Smith, Daniel K. Borger, , David Shechter

This study identifies TTLL4 as a therapeutic target in NPM1-mutated AML by showing its role in stabilizing NPM1c and promoting differentiation block, with a small molecule inhibitor demonstrating efficacy.

bioRxiv · Apr 7, 2025 · PreprintCancer Biology