Soban Umar

This study identifies subclinical liver dysfunction clusters in PAH patients and links them to pulmonary vascular resistance and immune signaling changes.

The paper investigates the role of hepatic MYDGF in pulmonary arterial hypertension, showing its protective effects in experimental models but paradoxical associations in human data.

This study shows that pulmonary hypertension increases microglia and astrocyte density, reduces neuronal density, and causes TDP-43 mislocalization in both rat and human brain tissue.

This study shows that targeting Snai1 in the right ventricle rescues pulmonary hypertension-induced failure by reducing EndMT, fibrosis, and FMT through a LOXL2-dependent mechanism.

The paper identifies a Tm4sf1-marked endothelial stem/progenitor cell subpopulation in rat lungs associated with PAH and shows its relevance to human PAH through transcriptomic analysis.