Rushika M. Perera

This study identifies a multi-subunit autophagic capture complex that degrades ER-stalled MHC-I in pancreatic cancer, reducing immunogenicity.

This study identifies hypoxia-induced proteolytic remodeling of cell surface and secreted proteins in PDAC cell lines, highlighting potential biomarkers and therapeutic targets.

This study identifies PCSK9 as a key determinant of metastatic organ preference in pancreatic cancer by regulating cholesterol acquisition and utilization in liver versus lung environments.

The paper identifies LyLAP as a key enzyme for lysosomal degradation of transmembrane proteins, showing its role in maintaining endocytic activity and lysosomal stability in pancreatic cancer.

The paper identifies RBM42 as a key regulator of MYC translation in PDAC, showing its role in oncogenic transcript regulation and tumor growth.