Author

Thomas H. H. Jordan

École Polytechnique Fédérale de LausanneORCID 0000-0001-8037-9396Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

George McDonald ChurchiD· 1 shared Jorge A. MarchandiD· 1 shared Jörn PieliD· 1 shared Kamesh NarasimhaniD· 1 shared Merrick Pierson SmelaiD· 1 shared Rosalie Lipsh-SokolikiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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1 shared paperBioinformatics

George McDonald ChurchORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintNov 3, 2026

Mapping and Probing the Substrate Scope of a Ketoamide-Forming Splicease by Computational Design

Thomas Henri Jordan, Rosalie Lipsh-Sokolik, Jörn Piel

The paper uses computational methods to design and evaluate splicease variants for generating diverse ketoamide substrates, finding that top-scoring peptides are spliced more efficiently than single-point mutants.

DOI 10.64898/2026.11.03.763875

protein structureprotein sequence

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BioinformaticsNucleic Acids ResearchPeer-reviewedAug 21, 2020

TBDB: A database of structurally annotated T-box riboswitch-tRNA pairs

Jorge A. Marchand, Merrick Pierson Smela, Thomas H. H. Jordan…·George McDonald Church

TBDB provides a database of structurally annotated T-box riboswitch-tRNA pairs, offering the largest collection of sequence and structural annotations for this regulatory RNA family.

20 citations

bacteria (other)experimental assay

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