Ruth A. Kelly

The paper identifies mitochondrial dysfunction in a glaucoma model using single-cell analysis and shows that vitamin B3 treatment protects against IOP elevation.

The paper identifies resident tissue macrophages as critical for maintaining intraocular pressure homeostasis by regulating extracellular matrix turnover in the trabecular meshwork.

The paper performs transcriptomic analyses of Schlemm's canal endothelial cells to reveal their lymphatic identity, three major cell states, and interactions with trabecular meshwork cells.