Author

Lucienne V. Ronco

Broad InstituteORCID 0000-0001-8045-3314Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Aaron N. Chang· 1 shared Alan Robertson· 1 shared Alice H. BergeriD· 1 shared Alykhan F. Shamji· 1 shared Andrew A. TubelliiD· 1 shared Angela M. CacaceiD· 1 shared Angela Norie BrooksiD· 1 shared Anita VrciciD· 1 shared

Activity by Year

2017-2020 · peak 1/yr

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10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Aaron N. Chang

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2 papers

Recent·Most cited

Developmental BiologyJournal of Pharmacology and Experimental TherapeuticsPeer-reviewedJun 23, 2020

P38α Regulates Expression of DUX4 in Facioscapulohumeral Muscular Dystrophy

Luis Alejandro Rojas, Erin Valentine, Anthony Accorsi…·Owen B. Wallace

This study identifies p38 as a regulator of DUX4 expression in FSHD, showing that p38 inhibitors reduce DUX4 and cell death in patient-derived myotubes.

44 citations

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsCellPeer-reviewedNov 1, 2017

A Next Generation Connectivity Map: L1000 Platform And The First 1,000,000 Profiles

Aravind Subramanian, Rajiv Narayan, Steven M. Corsello…·Todd R. Golub

The paper introduces the L1000 platform, a high-throughput gene expression profiling method, and reports 1.3 million perturbational profiles expanding the Connectivity Map for drug mechanism discovery and functional annotation.

3,517 citationstop 1%

bulk RNA-seqstatistical model

𝕏 PostBluesky